Skip to main content
. Author manuscript; available in PMC: 2013 Jan 1.
Published in final edited form as: Crit Care Med. 2012 Jan;40(1):208–215. doi: 10.1097/CCM.0b013e31822e9d31

Table 2.

Hypertonic saline or mannitol use for ≥ 2 days (N = 6,093 with length of stay ≥ 2 days), by hospital and injury characteristics and ICP monitoring

Hypertonic Saline, n(row%) X2p Mannitol, n(row%) X2p
n = 1,191 of 6,093 n = 1,204 of 6,093
Hospital ACSa Trauma level <0.001 < 0.001
I (n = 1,983) 388(20) 454(23)
II (n = 520) 59(11) 84(16)
none (n = 3,590) 744(21) 666(19)
Injury Type
Any ICHb vs. none 931(21) < 0.001 936(22) < 0.001
    (n = 4,347)
Any skull fracture vs. none 695(21) 0.009 707(21) 0.004
    (n = 3,350)
EDHc, no fracture (n = 220) 28(13) 0.009 24(11) 0.001
SAHd, no fracture (n = 536) 102(19) 0.752 100(19) 0.502
SDHe, no fracture (n = 1,232) 238(19) 0.821 273(22) 0.018
Head/Neck AISf < 0.001 < 0.001
3 (n = 3,040) 532(18) 521(17)
4 (n = 1,931) 385(20) 369(19)
5–6 (n = 1,122) 274(24) 314(28)
ISSg < 0.001 < 0.001
< 15 (n = 2,302) 389(17) 401(17)
≥ 15 (n = 3,791) 802(21) 803(21)
ICPh Monitor < 0.001 < 0.001
Yes (n = 2,248) 893(40) 899(40)
No (n = 3,845) 298(8) 305(8)
a

ACS = American College of Surgeons, Pediatric Trauma Designation

b

ICH = Intracranial hemorrhage

c

EDH = epidural hematoma without skull fracture (ICD-9-CM diagnosis codes 852.4 and 852.5)

d

SAH = subarachnoid hemorrhage without skull fracture (ICD-9-CM diagnosis codes 852.0 and 852.1)

e

SDH = subdural hemorrhage without skull fracture (ICD-9-CM diagnosis codes 852.2 and 852.3)

f

AIS = Abbreviated Injury Scale score, Head/Neck body region, derived using ICDMAP-90

g

ISS = Injury Severity Score, derived using ICDMAP-90