Skip to main content
. Author manuscript; available in PMC: 2013 Jan 1.
Published in final edited form as: Crit Care Med. 2012 Jan;40(1):208–215. doi: 10.1097/CCM.0b013e31822e9d31

Table 3.

Interrupted time series models for osmolar agent use for ≥ 2 days in the first week after injury

Hypertonic Saline Mannitol
% (95% CI) % (95% CI)
Before 9/2000 11.69 (11.20 to 12.17) 21.14 (20.57 to 21.70)
Slope, per month (9/00-6/03) 0.053 (0.031 to 0.075) 0.13 (0.11 to 0.16)
Change with guidelines 2.97 (2.49 to 3.44) −4.47 (−4.99 to −3.95)
Slope, per month (1/04-12/08) 0.16 (0.13 to 0.19) −0.24 (−0.27 to −0.22)