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Non-neurologic adverse events that were possibly, probably or definitely attributed to IT topotecan in 20 eligible patients*
| Event | Grade | |||
|---|---|---|---|---|
| 1 | 2 | 3 | 4 | |
| Fatigue | 1 | - | - | - |
| Fever | 1 | 2 | - | - |
| Weight Loss | - | 1 | - | - |
| Injection Site Reaction | - | 1 | 1 | - |
| Infection/Febrile Neutropenia | - | - | 1 | 1 |
| Pain | 1 | 1 | 1 | - |
| Dermatologic | 1 | - | - | - |
| Gastrointestinal | 5 | 4 | - | 1 |
| Hepatic | 1 | - | 3 | - |
| Metabolic | 2 | 1 | - | - |
| Hematologic | - | 2 | 1 | 3 |
More than 1 event may have occurred in the same patient
