Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Depiction of the general reaction catalyzed by the ligase members of the ATP-grasp superfamily of enzymes. The asterisks represent labeled oxygen atoms of the carboxylic acid and demonstrate the fate of these atoms during the course of the reaction. Notably, one oxygen atom is incorporated into phosphate suggesting the presence of an acylphosphate intermediate.
