. Author manuscript; available in PMC: 2012 Dec 1.

Published in final edited form as: Nat Rev Rheumatol. 2011 Sep 27;7(12):691–699. doi: 10.1038/nrrheum.2011.132

Table 1.

Neutrophil antimicrobial peptides

Peptide	Localization
Azurocidin	Primary granules Secretory vesicles
Bactericidal permeability increasing protein	Primary granules
Cathelicidin (LL-37)	Secondary granules NETs
Cathepsin G	Primary granules NETs
Elastase	Primary granules NETs
Histones	Nucleus NETs
HNPs	Primary granules NETs
Lactoferrin	Secondary granules
Lysozyme	Primary granules Secondary granules
Neutrophil gelatinase-associated lipocalin	Secondary granules
Peptidoglycan recognition proteins	Tertiary granules

Abbreviations: HNPs, human neutrophil peptides; NETs, neutrophil extracellular traps.