Figure 2.

Bridge nodes associated with glycine, L-glutamic acid, and haloperidol – GRIN2A, GRIN2B, GRIN2C, GRIN3B, DRD1, and DRD2. Gene targets are light grey circles, while drugs are dark grey v-shapes. All of the ionotropic glutamate receptors are of the NMDA family. DRD1 and DRD2 are dopamine receptors. The dashed circles denote the corresponding gene network clusters. A more detailed network is shown in Figure 1.