Table 1.
Patient Characteristics
| Variable | Cases | Controls | P-value |
|---|---|---|---|
| Study patients, n | 573 | 1,719 | |
| Age, mean (± SD), years | 71.7 (± 13.5) | 71.7 (± 13.5) | 1.0 |
| Women, n (%) | 272 (47.4) | 822 (47.8) | 0.92 |
| Ethnicity, n (%) | |||
| White | 455 (79.4) | 1,381 (80.3) | 0.27 |
| Black | 56 (9.8) | 133 (7.7) | |
| Hispanic | 28 (4.9) | 76 (4.4) | |
| Other (includes unknown) | 34 (5.9) | 129 (7.5) | |
| English is the primary language, n (%) | 521 (90.8) | 1,580 (91.9) | 0.51 |
| Health insurance, n (%) | |||
| Private | 110 (19.2) | 475 (27.6) | 0.0002 |
| Medicare | 414 (72.3) | 1,149 (66.8) | |
| Medicaid | 42 (7.3) | 83 (4.8) | |
| Uninsured | 7 (1.2) | 12 (0.7) | |
| HEMORR2HAGES score, mean (± SD) | 2.1 (1.5) | 2.1 (± 1.5) | 0.88 |
| Serum creatinine, mean (± SD), mg/dL | 2.3 (1.9) | 2.0 (± 1.6) | 0.0012 |
| Platelet count < 100,000 / μl, n (%) | 127 (22.2) | 360 (20.9) | 0.58 |
| Liver disease, n (%) | 17 (3.0) | 31 (1.8) | 0.13 |
| Alcohol abuse, n (%) | 9 (1.6) | 51 (3.0) | 0.097 |
| Malignancy, n (%) | 178 (31.1) | 587 (34.1) | 0.19 |
| Prior hemorrhage, n (%) | 28 (4.9) | 25 (1.5) | < 0.0001 |
| Uncontrolled Hypertension, n (%) | 11 (1.9) | 38 (2.2) | 0.81 |
| Anemia, n (%) | 215 (37.5) | 486 (28.3) | < 0.0001 |
| Dementia / Parkinson’s disease, n (%) | 50 (8.7) | 254 (14.8) | 0.0003 |
| Prior stroke, n (%) | 155 (27.1) | 479 (27.9) | 0.75 |
| Complex warfarin regimen, n (%) | 65 (11.3) | 193 (11.2) | 1.0 |