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. 2008 Sep 24;6:e0103. doi: 10.1199/tab.0103

Figure 20.

Figure 20.

GA-GID1-DELLA Binding Promotes SLY1-DELLA Interaction and DELLA Degradation.

GA-GID1 binding to the DELLA domain may trigger conformational changes that enhance SLY1 (a subunit of the SCFSLY1 complex) binding to the GRAS domain (in the DELLA protein). Once recruited by SLY1, DELLA will be polyubiquitinated and then degraded via the ubiquitin-proteasome pathway.