Table 2.
Alternative splicing events | SE* | RI† | A5E‡ | A3E§ | MXE∥ |
---|---|---|---|---|---|
Original novel exons in ENSG | 968 | 691 | 268 | 332 | 15 |
% of total (1,873) | 52% | 37% | 14% | 18% | < 1% |
Updated novel exons in ENSG | 623 | 629 | 197 | 235 | 8 |
% of total (1,384) | 45% | 45% | 14% | 17% | < 1% |
Novel AS exons in NTCs | 223 | 0 | 138 | 109 | 7 |
% of total (421) | 53% | 0 | 33% | 26% | 1% |
“Original”: novel exons identified relative to Ensembl v56. “Updated”: novel exons identified relative to the most recent databases including Ensembl v61, UCSC KnownGenes and RefSeq genes. Note that one exon may be associated with multiple types of AS. Such exons are counted into all applicable types. (Thus, the % values for all categories may not sum to 100%.)
SE: Skipped exon
RI: Retained intron
A5E: Alternative 5' splice site exon
A3E: Alternative 3' splice site exon
MXE: Mutually exclusive exon