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The Early Endomembrane System: ER and Golgi.
(A) The ER is typically observed as a reticulate pattern that ramifies throughout the cytosol, here visualized by confocal microscopy in a leaf epidermal cell expressing GFP-Calnexin (see: Irons et al., 2003). Early Golgi markers, such as GFP-ERD2 (the KDEL-receptor; see Boevink et al., 1998) show bright spots corresponding to the Golgi stacks (arrow), but also have a small percentage of protein that is also found in the ER (open arrow).
