The Arabidopsis complement of transcription factors. Gene families are represented by circles, whose size is proportional to the number of members in the family. Domains that have been shuffled, and that therefore “connect” different groups of transcription factors are indicated with rectangles, whose size is proportional to the length of the domain. DNA binding domains are colored; other domains (usually protein-protein interaction domains) are shown with hatched patterns. Dashed lines indicate that a given domain is a characteristic of the family or subfamily to which it is connected. Gene names are written in italics. Whereas many of the indicated domain shuffling events are specific to plants, others likely predate the appearance of the three distinct eukaryotic kingdoms (for details, see Riechmann et al., 2000). This figure is an expanded and updated version of Figure 1 in Riechmann et al. (2000).