Table 1.

Gene expression of Aβ degrading enzymes in NDC and DC SH-SY5Y cells treated with TNF-α

TNF-α	IDE		ACE		NEP		ECE-1
	NDC	DC	NDC	DC	NDC	DC	NDC	DC
Control	*1	1	1	1	1	1	1	1
	(0.78-1.29)	(0.76-1.31)	(0.71-0.41)	(0.89-1.12)	(0.74-1.36)	(0.63-1.58)	(0.77-1.3)	(0.77-1.3)
1 ng,	1.12	1.13	0.83	1.16	1.13	1.03	1.07	1.34
15 min	(0.89-1.41)	(0.9-1.43)	(0.55-1.26)	(0.97-1.37)	(0.88-1.46)	(0.51-2.1)	(0.74-1.54)	(0.98-1.84)
10 ng,	1.25	0.97	0.88	1.26	1.04	1.08	1.12	1.24
15 min	(1.1-1.43)	(0.97-1.08)	(0.68-1.14)	(0.96-1.65)	(0.78-1.38)	(0.51-2.3)	(0.96-1.3)	(0.95-1.62)
50 ng,	1.39	0.92	0.94	0.82	1.19	0.92	1.13	1.12
15 min	(1.12-1.71)	(0.72-1.17)	(0.61-1.45)	(0.63-1.07)	(0.79-1.8)	(0.39-2.18)	(0.96-1.34)	(0.76-1.64)
1 ng,	1.14	1.28	0.94	1.31	1.36	1.44	1.06	1.31
3 h	(1.04-1.24)	(0.99-1.66)	(0.61-1.45)	(1.01-1.7)	(1.11-1.67)	(0.79-2.6)	(0.87-1.28)	(1.09-1.57)
10 ng,	1.28	1.02	0.80	1.49	1.49	1.58	1.21	1.44
3 h	(1.13-1.44)	(0.7-1.49)	(0.6-1.06)	(1.29-1.72)	(1.22-1.82)	(0.87-2.84)	(0.93-1.57)	(1.11-1.87)
50 ng,	1.15	0.95	0.98	1.56	1.54	1.64	1.40	1.53
3 h	(0.98-1.34)	(0.65-1.41)	(0.82-1.18)	(1.15-2.12)	(1.15-2.07)	(0.85-3.15)	(1.14-1.72)	(1.16-2.03)

^*Numbers are the geometric means (with 95% confidence intervals) of the fold change in gene expression in each set of experiments.