TABLE 2.
Distribution of PON3 genotypes in the control group and HIV-infected patients
| Genotype frequency (%) |
PON3 (mg/l) |
||||
| Polymorphism | Control | HIV | Control | HIV | |
| PON3-567a | CC | 59.8 | 61.7 | 1.83 (0.45) | 5.97 (0.21) |
| CT | 36.4 | 32.1 | 1.68 (0.41) | 6.19 (0.31) | |
| TT | 3.8 | 6.3 | 1.56 (0.28) | 5.51 (0.55) | |
| PON3-665a | AA | 59.6 | 61.7 | 1.83 (0.45) | 5.97 (0.21) |
| AG | 36.6 | 32.1 | 1.68 (0.40) | 6.19 (0.31) | |
| GG | 3.8 | 6.3 | 1.56 (0.28) | 5.51 (0.55) | |
| PON3-746a | CC | 59.7 | 61.5 | 1.83 (0.44) | 5.98 (0.21) |
| CT | 36.5 | 31.8 | 1.67 (0.41) | 6.21 (0.32) | |
| TT | 3.8 | 6.6 | 1.56 (0.27) | 5.45 (0.52) | |
| PON3-4105 | GG | 61.7 | 64.8 | 1.82 (0.45) | 5.95 (0.20) |
| GA | 35.3 | 30.0 | 1.68 (0.40) | 6.18 (0.32) | |
| AA | 3.0 | 5.2 | 1.56 (0.32) | 5.89 (0.66) | |
| PON3-4970 | TT | 62.7 | 64.5 | 1.82 (0.45) | 5.99 (0.20) |
| TG | 34.8 | 30.7 | 1.69 (0.39) | 6.14 (0.32) | |
| GG | 2.5 | 4.9 | 1.51 (0.31) | 5.54 (0.60) | |
| PON3-4984 | AA | 62.4 | 64.6 | 1.81 (0.46) | 5.97 (0.20) |
| AG | 34.8 | 30.5 | 1.69 (0.39) | 6.08 (0.32) | |
| GG | 2.8 | 4.9 | 1.51 (0.31) | 5.54 (0.60) | |
a
Polymorphisms associated with significant changes (P < 0.05) in the control group but not in HIV-infected patients.