Fig. 4.

Misshapen nuclei in Fntb^Δ/Δ hepatocytes. (A) Immunohistochemical staining of primary hepatocytes from Fntb^+/+ and Fntb^Δ/Δ mice with an antibody against lamin A (green). (B) Frequency of misshapen nuclei in Fntb^+/+ and Fntb^Δ/Δ hepatocytes. Bars indicate the percentage of cells with misshapen nuclei; the number of cells harboring nuclear blebs and the total number of cells examined are recorded within each bar. Error bars indicate SEM for results with different cell preparations of the same genotype (n = 4/group).