Fig. 7.

Electron micrographs of livers from Pggt1b^+/+ and Pggt1b^Δ/Δ mice (A–F). Pggt1b^Δ/Δ livers exhibit dilated bile canaliculi (B), increased amounts of glycogen (D), smaller and darker-staining mitochondria (D, F), and reduced amounts of rough endoplasmic reticulum (F). BC, bile canaliculus; D, space of Disse; Gl, glycogen; M, mitochondria; Nu, nucleus; RER, rough endoplasmic reticulum. Magnification in panels A–B, ×14,000; scale bar, 2.0 μm. Magnification in panels C–D, ×23400; scale bar, 1.0 μm. Magnification in panels E–F, ×37,400; scale bar, 1.0 μm.