TABLE 2.
Wild-type | Pggt1b | P | |
ALT (U/L) | 39 ± 5 | 517 ± 91 | <0.0001 |
AST (U/L) | 159 ± 36 | 321 ± 64 | <0.0001 |
ALP (U/L) | 51 ± 4 | 350 ± 34 | <0.0001 |
CHOL (mg/dl) | 80 ± 16 | 121 ± 23 | NS |
GLU (mg/dl) | 296 ± 27 | 211 ± 21 | NS |
TRIG (mg/dl) | 99 ± 10 | 87 ± 10 | NS |
DBILI (mg/dl) | 0.1 ± 0.01 | 32 ± 3 | <0.0001 |
TBILI (mg/dl) | 0.2 ± 0.02 | 35 ± 7 | <0.0001 |
n = 8 mice/group, 8 weeks of age. Mean ± SEM.
CHOL, cholesterol; DBILI, direct bilirubin; GLU, glucose; NS, not significant; TBILI, total bilirubin; TRIG, triglyceride.