TABLE 4.
Wild-type | Fntb Pggt1b | P | |
ALT (U/L) | 39 ± 5 | 1201 ± 48 | <0.0001 |
AST (U/L) | 159 ± 36 | 1487 ± 72 | <0.0001 |
ALP (U/L) | 51 ± 4 | 1501 ± 47 | <0.0001 |
CHOL (mg/dl) | 80 ± 16 | 69 ± 8 | NS |
GLU (mg/dl) | 296 ± 27 | 87 ± 11.3 | NS |
TRIG (mg/dl) | 99 ± 10 | 52 ± 7.6 | NS |
DBILI (mg/dl) | 0.1 ± 0.02 | 9.45 ± 3.62 | <0.0001 |
TBILI (mg/dl) | 0.2 ± 0.01 | 13.7 ± 3.41 | <0.0001 |
CHOL, cholesterol; GLU, glucose; DBILI, direct bilirubin; NS, not significant; TBILI, total bilirubin; TRIG, triglyceride.
n = 8 mice/group, 6–8 weeks of age. Mean ± SEM.