Table 3.
Correlations between Markers and Brain Status at Baseline
MARKER | NBPV | WM | GM | CSF | MD | FA |
---|---|---|---|---|---|---|
Eotaxin | -.24 | -.06 | -.48 | .30 | -.38 | -.54 |
GM-CSF | --- | --- | --- | --- | --- | --- |
IFNγ | † | † | † | † | † | † |
IL-10 | --- | --- | --- | --- | --- | --- |
IL-12p40 | .12 | .02 | -.02 | -.12 | -.23 | -.06 |
IL-12P70 | --- | --- | --- | --- | --- | --- |
IL-13 | --- | --- | --- | --- | --- | --- |
IL-15 | --- | --- | --- | --- | --- | --- |
IL-1α | † | † | † | † | † | † |
IL-1β | --- | --- | --- | --- | --- | --- |
IL-2 | --- | --- | --- | --- | --- | --- |
IL-3 | --- | --- | --- | --- | --- | --- |
IL-4 | --- | --- | --- | --- | --- | --- |
IL-5 | --- | --- | --- | --- | --- | --- |
IL-6 | --- | --- | --- | --- | --- | --- |
IL-7 | --- | --- | --- | --- | --- | --- |
IL-8 | -.05 | -.12 | -.20 | .230 | -.20 | -.23 |
IP-10 | -.31 | -.15 | -.44 | .31 | .30 | -.27 |
MCP-1 | -.49 | -.24 | -.53 | .55(*) | -.23 | -.69* |
MIP-1α | .02 | -.09 | -.27 | .14 | -.34 | -.14 |
RANTES | .27 | .11 | .52 | -.42 | .01 | .30 |
TNFα | --- | --- | --- | --- | --- | --- |
Abbreviations: NBPV:normalized parenchymal brain volume, WM: white matter, GM: gray matter, CSF: cerebrospinal fluid, MD: mean diffusivity, FA: fractional anisotropy.
Beyond limits of detection (low) in at least half of the subjects.
Beyond limits of assay detection (uniformly low) in all subjects.
p <.05;
p<.10