Table 3.
Binding Energy and Constant Inhibition of Tested Compounds
| |
Estimated binding energy for |
|
||
|---|---|---|---|---|
| Receptor/ligand | Aromatase | NFκB (p50) | NFκB (p100) | Estimated Ki(μM) |
| Naringenin | −7.22 | ND | ND | 4.87031×10−6 |
| Capsaicin | −6.42 | ND | ND | 1.88883×10−5 |
| Capsazepine | −7.95 | ND | ND | 1.41392×10−6 |
| Letrozole | −6.41 | ND | ND | 1.92110×10−5 |
| Capsaicin | ND | ND | −5.22 | 1.44260×10−4 |
| Capsazepine | ND | ND | −6.33 | 2.19996×10−5 |
| TPCK | ND | ND | −6.49 | 1.67759×10−5 |
| Capsaicin | ND | −5.13 | ND | 1.68023×10−4 |
| Capsazepine | ND | −6.02 | ND | 3.71973×10−5 |
| TPCK | ND | −6.48 | ND | 1.70626×10−5 |
Ki, inhibition constant; ND, not determined.