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Distribution of oligomers in wild-type DISC1 and NDEL1. a, analytical ultracentrifugation data were fitted using the Monte Carlo simulation method using Ultrascan software. Wild-type DISC1 has been fitted to two oligomeric populations, a dimer (∼270 kDa) and an octamer (∼1.1 MDa). b, Monte Carlo data fitting of analytical ultracentrifugation data on NDEL1 predicts the existence of a unique tetramer population (∼200 kDa).
