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. 2011 Oct 13;286(51):44266–44276. doi: 10.1074/jbc.M111.271593

FIGURE 7.

FIGURE 7.

Distribution of oligomers with the MBP-DISC1-S704C variant. Analytical ultracentrifugation data of MBP-DISC1-S704C were fitted using Monte Carlo simulation method (Ultrascan software). The data have been fitted to two oligomeric populations, a dimer (∼240 kDa) and an oligomer that is higher than a nonamer (∼1.3 MDa). The observed molecular weight of wild-type DISC1 is indicated by the dotted line.