FIGURE 2.
The Δstp1 mutant shows decreased survival during GBS systemic infections. Five 6-week-old female CD-1 mice were intravenously injected with 3 × 107 cfu of WT or the Δstp1 mutant. At ∼24–48 h postinfection, blood, spleen, and brain were harvested from the infected mice, and cfu were enumerated. A significant decrease in cfu was observed in the blood (see A; p < 0.05), spleen (see B; p < 0.05), and brain (see C; p < 0.05) of mice infected with the Δstp1 mutant when compared with mice infected with the WT strain A909.