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. 2011 Sep 13;30(22):4628–4641. doi: 10.1038/emboj.2011.331

Figure 7.

Figure 7

Transmission electron microscopy confirms repression of autophagy by miR-101 overexpression or Stathmin knockdown. (A–C) Representative images of MCF-7 cells transfected for 72 h as indicated, and treated for 2 h with 200 nM rapamycin prior to fixation. Top panel: overview images (× 3400 magnification). Scale bars represent 5 μM. Bottom panel: close-up images (× 24 500 magnification) of cytoplasmic regions containing autophagosomes (denoted by white arrowheads). Scale bars represent 1 μM. (D) The data were quantified by counting the number of autophagosomes per cross-sectioned cell (scramble n=30, miR-101 n=25, siStathmin n=25). ***P<0.0005.