Table 2. Expression profile of fibrogenic gene mRNA in infected with recombinant HSV-1 cultures and mock infected cultures from healthy donors.
MEANS±SD | Infected(n = 4) | Mock(n = 4) | Ratio of means (infected/mock) | P value |
SDF-1a | 0.69±0.67 | 1.00±1.00 | 0.67 | 0.795 |
SDF-1b | 1.12±1.12 | 0.9±0.16 | 1.23 | 0.864 |
CXCR4 | 0.74±0.31 | 1.57±0.25 | 0.47 | 0.101 |
VEGF | 1.06±0.52 | 64.36±39.48 | 0.02 | 0.184 |
TGF-β1 | 0.48±0.24 | 0.57±0.31 | 0.84 | 0.828 |
FGF | 1.06±0.52 | 64.36±39.48 | 0.02 | 0.184 |
MMP2 | 0.39±0.26 | 0.41±0.19 | 0.96 | 0.961 |
MMP9 | 0.17±0.07 | 0.38±0.14 | 0.45 | 0.265 |
CCR7 | 0.31±0.14 | 3.94±2.72 | 0.08 | 0.254 |
CCL19 | 17.83±8.92 | 2.09±0.87 | 8.53 | 0.154 |
CCL21 | 27000±2645.75 | 15000±2645.75 | 1.8 | 0.033 |
TLR3 | 33.33±33.33 | 21.33±8.59 | 1.56 | 0.745 |
TLR8 | 0.5±0.16 | 0.23±0.28 | 0.95 | 0.939 |
TLR9 | 5.06±4.29 | 49.31±24.46 | 0.10 | 0.149 |