Table 3. Expression profile of mRNA transcript levels of axis in infected with recombinant HSV-1 from IPF patients compared to healthy donors.
Infected with recombinant HSV-1 cultures | ||||
Gene | IPF (MEANS) | Healthy Donors (MEANS) | Ratio of the means (IPF/Donors) | p value |
SDF-1a | 11.97 | 0.69 | 17.35 | 0.348 |
SDF-1b | 0.09 | 1.12 | 0.08 | 0.568 |
CXCR4 | 0.00 | 0.74 | 0.001 | 0.349 |
VEGF | 0.04 | 1.06 | 0.04 | 0.05 |
TGF-β1 | 0.01 | 0.48 | 0.01 | 0.439 |
FGF | 0.03 | 1.06 | 0.03 | 0.463 |
MMP2 | 0.00 | 0.39 | 0.01 | 0.132 |
MMP9 | 88.13 | 0.17 | 518.41 | 0.324 |
CCR7 | 6.61 | 0.31 | 21.32 | 0.7 |
CCL19 | 0.00 | 17.83 | 0.0001 | 0.246 |
CCL21 | 0.00 | 27000 | 0.00 | 0.001 |
TLR3 | 0.70 | 33.33 | 0.02 | 0.980 |
TLR8 | 0.00 | 0.5 | 0.00 | 0.014 |
TLR9 | 0.00 | 5.06 | 0.00 | 0.05 |