Table 1.
Treatment | Control |
XE991 |
||
---|---|---|---|---|
Membrane potential (mV) | Input resistance (GΩ) | Membrane potential (mV) | Input resistance (GΩ) | |
Males | ||||
Fed | −71.5 ± 1.6** | 0.64 ± 0.12 | −62.5 ± 2.9a | 1.02 ± 0.18a |
Fasted | −64.8 ± 1.6 | 0.65 ± 0.12 | −57.1 ± 1.9b | 0.81 ± 0.09 |
Refed | −68.5 ± 0.9 | 0.63 ± 0.07 | −58.3 ± 1.5d | 0.97 ± 0.11b |
Females | ||||
Oil | −68.1 ± 1.8* | 0.65 ± 0.09 | −62.7 ± 1.3a | 1.19 ± 0.28 |
E2 | −72.4 ± 1.1 | 0.68 ± 0.08 | −62.4 ± 2.0c | 1.0 ± 0.12b |
Fasted E2 | −65.6 ± 1.5*** | 0.63 ± 0.06 | −58.8 ± 2.0a | 0.79 ± 0.12 |
ap < 0.05, bp < 0.01, cp < 0.001, and dp < 0.0001 denote control to XE991 comparisons.
*p < 0.05, **p < 0.01, and ***p < 0.001 denote fed versus fasted comparisons in males, and oil and fasted E2 compared with E2 in females. For males: fed n = 11; fasted n = 17; refed n = 10. For females: oil n = 14; E2 n = 15; fasted E2 n = 11.