Table 1.
Characteristics of WIHS participants at HAART initiation by CKD status
| Characteristic | No CKD (n=1381) | Prevalent CKD (n=44) |
|---|---|---|
| Age, mean years (SD)a | 38.9 (8.1) | 44.0 (9.1) |
| Black, n (%) | 774 (56) | 28 (64) |
| Injection drug use, n (%) | 489 (36) | 20 (46) |
| Body mass index, median kg/m2 (IQR) | 26.1 (22.8 – 30.6) | 23.8 (20.5 – 32.1) |
| CD4+ cell count, median cells/mm3 (IQR) a,b | 271 (149 – 419) | 171 (65 – 322) |
| HIV-1 RNA level, median copies/ml (IQR) b | 17,000 (2300 – 80,000) | 19,000 (935 – 115,000) |
| Serum albumin, median mg/dl (IQR) a, b | 4.2 (3.9 – 4.4) | 3.6 (3.2 – 4.0) |
| Serum creatinine, median mg/dl (IQR) a | 0.8 (0.7 – 0.9) | 1.5 (1.3 – 3.2) |
| Estimated GFR, median ml/min/1.73 m2 (IQR) a | 92.6 (77.9 – 113.2) | 40.8 (19.5 – 52.9) |
| Hepatitis C antibody positive, n (%) | 505 (38) | 21 (48) |
| History of illness, n (%) | ||
| AIDS a | 812 (59) | 33 (75) |
| Diabetes mellitus a | 99 (9) | 9 (30) |
| Hypertension a | 622 (46) | 33 (75) |
The following were missing: CD4+ cell count (n=84), HIV-1 RNA level (n=86), serum albumin (n=122), hepatitis C antibody (n=41), diabetes (n=268) and hypertension (n=21).
a
P-value <0.05;
b
Values from visit just prior to HAART initiation