Table 2.
Tobit regression estimates for longitudinal MMSE as dependent variable and baseline sMG as the primary predictor
| Parameter | Estimate | StandardError | tValue | P-value | Lower 95% CL | Upper 95% CL |
|---|---|---|---|---|---|---|
| INTERCEPT | 6.3413 | 2.0902 | 3.0300 | 0.0027 | 2.2258 | 10.4567 |
| MONTH OF FOLLOW UP | -0.0177 | 0.0068 | -2.6100 | 0.0095 | -0.0310 | -0.0044 |
| BASELINE NEWMG | -0.0751 | 0.1750 | -0.4300 | 0.6683 | -0.4196 | 0.2695 |
| MONTH OF FOLLOW UP X BASELINE NEWMG | -0.0137 | 0.0063 | -2.1700 | 0.0311 | -0.0261 | -0.0013 |
| BASELINE MINI MENTAL | 0.8745 | 0.0487 | 17.9600 | <.0001 | 0.7787 | 0.9703 |
| FEMALE | 0.4839 | 0.2051 | 2.3600 | 0.0190 | 0.0802 | 0.8877 |
| YEARS OF EDUCATION | 0.0730 | 0.0255 | 2.8600 | 0.0045 | 0.0228 | 0.1232 |
| AGE | -0.0420 | 0.0168 | -2.5100 | 0.0127 | -0.0751 | -0.0090 |
| MONTH OF FOLLOW UP | -0.0181 | 0.0070 | -2.6000 | 0.0098 | -0.0319 | -0.0044 |
| BASELINE NEWMG | -0.0920 | 0.1762 | -0.5200 | 0.6022 | -0.4389 | 0.2550 |
| MONTH OF FOLLOW UP X BASELINE NEWMG | -0.0142 | 0.0064 | -2.2000 | 0.0285 | -0.0268 | -0.0015 |
| BASELINE MINI MENTAL | 0.8615 | 0.0497 | 17.3200 | <.0001 | 0.7636 | 0.9594 |
| FEMALE | 0.5699 | 0.2124 | 2.6800 | 0.0077 | 0.1517 | 0.9880 |
| YEARS OF EDUCATION | 0.0652 | 0.0260 | 2.5100 | 0.0128 | 0.0140 | 0.1163 |
| AGE | -0.0584 | 0.0172 | -3.3900 | 0.0008 | -0.0922 | -0.0245 |
| DIABETES | -0.1801 | 0.2131 | -0.8400 | 0.3989 | -0.5997 | 0.2395 |
| APOE4CH | -0.3898 | 0.1965 | -1.9800 | 0.0484 | -0.7767 | -0.0028 |
| BMI | -0.0135 | 0.0201 | -0.6700 | 0.5017 | -0.0532 | 0.0261 |
| INTERCEPT | 7.8554 | 2.4871 | 3.1600 | 0.0018 | 2.9560 | 12.7548 |
| MONTH OF FOLLOW UP | -0.0191 | 0.0070 | -2.7100 | 0.0072 | -0.0330 | -0.0052 |
| BASELINE NEWMG | -0.0522 | 0.1784 | -0.2900 | 0.7702 | -0.4036 | 0.2993 |
| MONTH OF FOLLOW UP X BASELINE NEWMG | -0.0135 | 0.0064 | -2.1100 | 0.0363 | -0.0262 | -0.0009 |
| BASELINE MINI MENTAL | 0.8453 | 0.0525 | 16.1100 | <.0001 | 0.7419 | 0.9487 |
| FEMALE | 0.6674 | 0.2203 | 3.0300 | 0.0027 | 0.2335 | 1.1014 |
| YEARS OF EDUCATION | 0.0685 | 0.0267 | 2.5600 | 0.0110 | 0.0158 | 0.1212 |
| AGE | -0.0450 | 0.0202 | -2.2300 | 0.0270 | -0.0848 | -0.0052 |
| DIABETES | -0.1608 | 0.2252 | -0.7100 | 0.4760 | -0.6044 | 0.2829 |
| APOE4CH | -0.2750 | 0.2053 | -1.3400 | 0.1817 | -0.6794 | 0.1294 |
| BMI | -0.0368 | 0.0228 | -1.6200 | 0.1075 | -0.0817 | 0.0081 |
| KIDNEY FUNCTION | 0.0106 | 0.0054 | 1.9600 | 0.0515 | -0.0001 | 0.0213 |
| INTERCEPT | 9.0411 | 2.8383 | 3.1900 | 0.0017 | 3.4445 | 14.6377 |
| MONTH OF FOLLOW UP | -0.0148 | 0.0074 | -2.0000 | 0.0464 | -0.0294 | -0.0002 |
| BASELINE NEWMG | 0.0649 | 0.1870 | 0.3500 | 0.7289 | -0.3038 | 0.4335 |
| MONTH OF FOLLOW UP X BASELINE NEWMG | -0.0170 | 0.0067 | -2.5300 | 0.0123 | -0.0303 | -0.0037 |
| BASELINE MINI MENTAL | 0.7946 | 0.0565 | 14.0700 | <0.0001 | 0.6832 | 0.9059 |
| FEMALE | 0.7769 | 0.2450 | 3.1700 | 0.0018 | 0.2939 | 1.2599 |
| YEARS OF EDUCATION | 0.0778 | 0.0301 | 2.5900 | 0.0103 | 0.0185 | 0.1371 |
| AGE | -0.0607 | 0.0225 | -2.7000 | 0.0075 | -0.1049 | -0.0164 |
| DIABETES | -0.3545 | 0.3300 | -1.0700 | 0.2840 | -1.0051 | 0.2962 |
| APOE4CH | -0.2447 | 0.2158 | -1.1300 | 0.2581 | -0.6702 | 0.1807 |
| KIDNEY FUNCTION | 0.0058 | 0.0054 | 1.0800 | 0.2829 | -0.0049 | 0.0165 |
| A1C | 0.0767 | 0.1543 | 0.5000 | 0.6196 | -0.2275 | 0.3809 |
| GLUCOSE | -0.0022 | 0.0034 | -0.6500 | 0.5166 | -0.0090 | 0.0045 |
| HDL | -0.0174 | 0.0077 | -2.2500 | 0.0257 | -0.0326 | -0.0021 |
| LDL | -0.0119 | 0.0072 | -1.6500 | 0.0996 | -0.0261 | 0.0023 |
| TOTAL CHOLESTEROL | 0.0136 | 0.0065 | 2.0900 | 0.0376 | 0.0008 | 0.0265 |
| EVER SMOKED | 0.1039 | 0.1822 | 0.5700 | 0.5690 | -0.2553 | 0.4631 |