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. Author manuscript; available in PMC: 2013 Jan 1.

Published in final edited form as: J Neurochem. 2011 Dec 2;120(2):302–313. doi: 10.1111/j.1471-4159.2011.07543.x

Table I. Atp8a1 overexpression causes an increase in Vmax for the PM-APLT activity in the N18 cells.

(paired t-test was used for the analysis of V_max and K_m values from three experiments)

Exp	Empty Vector in N18				Atp8a1 in N18
	K_m (nmole/μm²)	K_m(nmole/μm²) Mean± Std.Dev.	V_max (nmole/ min/μm²)	V_max (nmole/ min/μm²) Mean± Std.Dev.	K_m (nmole/μ m²)	K_m(nmole/μm²) Mean± Std.Dev.	V_max (nmole/ min/μm²)	V_max (nmole/ min/μm²) Mean± Std.Dev.
1	4.9	3.9±0.9	4.32	5.1±0.81	5.7	4.4±1 p=0.3269 (vector vs. Atp8a1)	9.23	8.3±0.8 p=0.004112 (vector vs. Atp8a1)
2	3.8		4.96		4.2		7.92
3	3.1		5.94		3.2		7.76

Exp	Fold Increase in Km in the presence of Atp8a1		Fold Increase in Vmax in the presence of Atp8a1
	Fold Increase	Mean± Std.Dev	Fold Increase	Mean± Std.Dev
1	1.16	1.1±0.066	2.14	1.7±0.42
2	1.11		1.60
3	1.03		1.31