Transient muscle paralysis did not alter periosteal surface changes (A; Ps.Ar) at the analyzed 2-D transverse cross-sections in Age-Matched (white diamond, partially obscured b overlying BTxA data) vs BTxA mice (black square, mean ± s.e.). In contrast, significant differences in cortical (Ct.Ar) and endocortical morphology (Ec.Ar) were identified at all but one cross-section examined in BTxA vs Age-Matched Control mice (*, significantly differences vs. BTxA, p<0.05).