Skip to main content
. Author manuscript; available in PMC: 2013 Jan 1.
Published in final edited form as: J Neurochem. 2011 Nov 11;120(2):239–247. doi: 10.1111/j.1471-4159.2011.07539.x

Figure 6. ERK1/2 activation is required for CNTF stimulated TH ubiquitination.

Figure 6

Sympathetic neurons were treated with CNTF for 30 min, with or without 10 μM U0126 to prevent ERK1/2 activation. TH was immunoprecipitated and immunoblotted with anti-ubiquitin antibody. Total TH levels were identified by immunoblot as a control. CNTF-induced phosphorylation of ERK1/2 was blocked by U0126, but total ERK1/2 was unchanged. Representative of at least 3 independent experiments.