The natural log plot of TH content in M17 cells, graphed as percentage of the TH present at time 0, is shown. Data are the mean of 3 independent experiments ± SEM; * p<0.05 vs. control. Each condition was assayed in triplicate for each experiment. Calculated half-life: Control 33.3±3.6 hr, CNTF 16.3±0.5* hr, CNTF+UO 27.0±3.5 hr, UO 28.3±2.4 hr, n=3 experiments.