Table 3.

Imaging results of multiple endocrine neoplasia type 1 patients with Cushing’s syndrome.

Patient ID	Pituitary Imaging	Adrenal Imaging	Other
Cushing's Disease Group
1	Heterogeneous enlarged pituitary 12 X 12 X 15 mm	Normal	ND
2	Neg	ND	ND
3	Neg	6 mm nodule; left adrenal	ND
4	Neg	Bilateral adrenal hyperplasia; possible nodular hyperplasia of right adrenal	ND
5	NA	NA	ND
6	Pituitary macroadenoma, with central necrosis, growing into left sphenoid sinus	Normal	Mass in pancreatic head
7	Multiple hypo-enhancing lesions on left, largest 4 mm; stalk deviation to right	2 cm left adrenal nodule	2 hepatic masses (a)
8	Neg	Bilateral adrenal hyperplasia	Right renal mass (b)
9	2–3 mm hypo-enhancing lesion on left	Right adrenal nodule left adrenal thickening	None
10	Fullness on right, no focal lesion.	ND	3 cm pancreatic mass
11	5–6 mm hypointense lesion on left	3 cm left adrenal nodule	None
ACTH-independent Cushing's, Adrenal Tumor Group
12	Neg	4 X 6 cm right adrenal mass	None
13	Neg	5 cm right adrenal mass	None
14	ND	ND	ND
Cushing's Syndrome from Unknown Etiology Group
15	Neg ( c)	NA (d)	NA (d)
16	6 mm lesion on right	NA (d)	NA (d)
17	Poorly defined lesion on right	Enlarged, nodular left adrenal	Neg chest CT
18	2–3 mm asymmetry on left	Slight bilateral hyperplasia	Multiple pulmonary nodules; small lesion in pancreatic tail
19	Neg	Diffuse bilateral nodular enlargement	Left pulm nodule vs. granuloma

^(a)masses were surgically confirmed hepatic adenomas.

^(b)renal mass was confirmed surgically to be an angiomyolipoma.

^(c)sella turcica imaging studies (c. 1971) normal at an outside institution.

^(d)imaging studies while patient with Cushing’s syndrome performed prior to NIH evaluation and results not available.

Abbreviations: Neg, negative; NA, result or data not available; ND, not determined.