Table 3.
Association of Body Mass Index at Age 50 Years With Prevalence of Peripheral Arterial Disease at the Baseline Examination, Cardiovascular Health Study, 1989–2007
| BMIa Measure | Sex and BMI Category |
All Participants |
Never Smokers in Good Healthb |
|||||||||
| PAD Prevalence |
Demographic Factor-Adjustedc |
Multivariable-Adjustedd |
PAD Prevalence |
Demographic Factor-Adjustedc |
||||||||
| Women (n = 3,114) | Men (n = 2,305) | % | No. With PAD/Total | PR | 95% CI | PR | 95% CI | % | No. With PAD/Total | PR | 95% CI | |
| Quartile | ||||||||||||
| 1 | <22.3 | <23.9 | 14 | 192/1,358 | 1 | Reference | 1 | Reference | 8 | 36/440 | 1 | Reference |
| 2 | 22.3–24.3 | 23.9–25.6 | 13 | 170/1,353 | 1.01 | 0.81, 1.25 | 0.97 | 0.80, 1.19 | 6 | 30/479 | 1.10 | 0.57, 2.13 |
| 3 | 24.4–26.9 | 25.7–27.7 | 15 | 201/1,354 | 1.13 | 0.93, 1.38 | 1.05 | 0.86, 1.27 | 10 | 50/489 | 1.72 | 0.95, 3.12 |
| 4 | ≥27.0 | ≥27.8 | 16 | 213/1,354 | 1.15 | 0.94, 1.40 | 1.04 | 0.86, 1.26 | 10 | 41/430 | 1.74 | 0.97, 3.14 |
| Continuous (per 5-unit increase) | 1.05 | 0.97, 1.14 | 1.00 | 0.92, 1.09 | 1.30 | 1.11, 1.51 | ||||||
Abbreviations: BMI, body mass index; CI, confidence interval; PAD, peripheral arterial disease; PR, prevalence ratio.
a
Weight (kg)/height (m)2.
b
Limited to persons who had never smoked, reported good, very good, or excellent health, and reported no unintentional weight loss of >10 pounds (>4.5 kg).
c
Adjusted for age, sex, race, and field center.
d
Adjusted for age, sex, race, field center, smoking status (current, former, or never smoker), pack-years of smoking, and self-reported health status (excellent, very good, good, fair, or poor).