Table 2.
Changes in NK cell function induced by MHV68 latencya
Granzyme B Expression By NK Cells | |
---|---|
Host | % NK cells that express granzyme B |
healthy adult humans | ~40b |
SPF mice | ~10 |
MHV68 latently infected mice | ~40 |
Protects Against RMA-S Lymphoma Transfer | |
Condition | Lethality |
Mock-infected | 80% |
MHV68 latently infected | 10% |
MHV68 latently infected, NK-depleted | 80% |