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. 2011 Dec 14;31(50):18391–18400. doi: 10.1523/JNEUROSCI.4550-11.2011

Figure 4.

Figure 4.

RGMb-deficient mice show retarded axonal regeneration following sciatic nerve crush. A, GAP-43 fluorescent immunohistochemistry demonstrates decreased axonal growth 48 h following sciatic nerve crush in RGMb KO mice compared with WT LMs; sciatic nerve crush injury was performed at postnatal day 8. Scale bar, 500 μm. B, Functional regeneration assessed using the pinch test shows decreased regeneration at 24 and 48 h postinjury in RGMb KO mice compared with WT LMs; sciatic nerve crush injury was performed at postnatal day 8. *p < 0.001.