Table 3.
Iron sucrose removal in a closed-loop system by high-flux or high-efficiency hemodialysis membranes over 240 minutes. (System B)
Iron Sucrose (Venofer®) | ||||
Study condition |
SBS % iron concentration change (mean ± SD) |
Khd (hr-1) (mean ± SD) |
Dialysate Iron Recovery (mg) (mean ± SD) |
Clearance† (ml/min) (mean ± SD) |
F80: 0 ml/hr UFR | -3.13 ± 0.06 | -0.0001 ± 0.0000 | 13.82 ± 13.34 | -0.76 ± 0.01 |
F80: 500 ml/hr UFR | -0.03 ± 1.15 | 0.0000 ± 0.0000 | 23.59 ± 3.96 | 0.05 ± 0.19 |
CA210: 0 ml/hr UFR | -1.41 ± 3.77 | -0.0001 ± 0.0002 | 5.47 ± 1.52 | -0.34 ± 0.92 |
CA210: 500 ml/hr UFR | -1.58 ± 3.08 | -0.0003 ± 0.0002 | 2.79 ± 1.89 | -1.08 ± 0.93 |
SBS = simulated blood solution; UFR = ultrafiltration rate; Khd = hemodialysis elimination rate; % = percent; † = Clearance values that are positive relate to accumulation of substance from the system; negative clearance values represent removal of substance