Figure 3.

Ex vivo monitoring of luminescent ATAK cells in infected mice serially after treatment. Mice were rendered neutropenic with cyclophosphamide and treated once intraperitoneally with ATAK cells. The mice were infected intravenously with sublethal inocula of S. aureus LAC, A. baumannii HUMC1, or C. albicans SC5314 or through lung inhalation of A. fumigatus AF293. At each time point, organs were harvested from 2 mice per group, plated, and imaged by IVIS. The experiment was repeated once (2–4 mice total per group).

Abbreviation: ATAK, activated transfected killer.