Table 3. Linear regression-derived associations between rs2298849, rs2282679, and rs10877012 and serum levels of 25(OH)D among African Americans.
| SNP | Comparison | betaa | p-value |
| Model type 1 b | |||
| rs2298849 | AA to GG | −3.62 | 0.005 |
| rs2282679 | (GT, GG combinedc) to TT | −2.53 | 0.03 |
| rs10877012 | GG to (GT, TT combinedc) | −2.11 | 0.04 |
| Model type 2 d | |||
| rs2298849 | AA to GG | −3.27 | 0.01 |
| rs2282679 | (GT, GG combinedc) to TT | −1.87 | 0.13 |
| rs10877012 | GG to (GT, TT combinedc) | −1.40 | 0.18 |
a
Interpreted as the average change in serum 25(OH)D level (ng/mL) associated with the genotype comparison shown in the table.
b
Three separate linear regression models including each SNP alone, adjusted for sex and percentage African ancestry.
c
Genotypes combined because less than five subjects had the homozygous variant genotype.
d
One linear regression model including the three SNPs together, adjusted for sex and percentage African ancestry.