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. 2011 Dec 21;6(12):e28908. doi: 10.1371/journal.pone.0028908

Table 2. Sensory neuron survival in vitro.

Control NGF GDNF Artemin NRTN
6 h (%) 100 100 100 100 100
1 d (%) 85.31±0.69 96.24±1.13* 92.38±2.06* 94.12±2.09* 81.95±5.23
4 d (%) 73.22±3.27 89.53±1.64* 87.71±1.80* 88.48±1.94* 76.16±4.43

The number of NeuN-positive neurons 6 h after plating was designated as 100%. Without growth factors (Control), approximately 15% of neurons died 1 d after plating and 27% died by 4 d. Application of NGF, GDNF and ARTN significantly increased neuron survival although NRTN was ineffective.

*p<0.05; Two way ANOVA, Dunnett's post-hoc test.