Table 2. Comparison of MYOC gene mutations and polymorphisms (with dbSNP accession numbers) observed among POAG patients from Chennai and Kanyakumari district of South India.
| Mutations | Polymorphisms | |||||||
|---|---|---|---|---|---|---|---|---|
| Location | Group | Gln48His ss295476454 | Ser331Thr ss295476451 | Thr353Ile ss295476455 | Pro370Leu ss295476453 | Asn480Lys ss295476456 | Thr325Thr ss295476450 | Try347tyr ss295476452 |
| Chennai | Patients n=101 | 2 | 0 | 1 | 0 | 1 | 0 | 0 |
| Controls n=101 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| KK District | Patients n=100 | 0 | 1 | 0 | 1 | 0 | 1 | 4 |
| Controls n=100 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |