Table 3.
Activation patterns identified between and within groups during memory trials
Trial; contrast | Talaraich coordinate
|
Region | Subregion | Brodmann area | t value | No. voxels | ||
---|---|---|---|---|---|---|---|---|
x | y | z | ||||||
Between-group contrast | ||||||||
Recollection trials–study trials | ||||||||
Control > MDD | 26 | −20 | −14 | Hippocampus | RHH | 3.679 | 1041 | |
−27 | −25 | −16 | Hippocampus / parahippocampal gyrus | LHH | 35 | 3.334 | 26 | |
Within-group contrasts | ||||||||
Recollection trials–study trials | ||||||||
MDD | 28 | −21 | −16 | Hippocampus | RHH | −3.393 | 5120 | |
−26 | −19 | −2 | Parahippocampal gyrus | −3.211 | 3718 | |||
−23 | −21 | −22 | Parahippocampal gyrus | 35 | −3.272 | 1083 | ||
Control | 23 | −15 | −15 | Hippocampus / parahippocampal gyrus | RHH | 28 | 4.480 | 8829 |
−21 | −12 | −15 | Hippocampus / parahippocampal gyrus | LHH | 28 | 4.291 | 5700 | |
−22 | −31 | −2 | Hippocampus / parahippocampal gyrus | LHT | 27 | −3.928 | 2759 | |
Habit trials–study trials | ||||||||
MDD | 31 | −42 | −6 | Parahippocampal gyrus | Posterior | 19 | 3.594 | 1901 |
27 | −20 | −2 | Parahippocampal gyrus | Anterior | −3.345 | 229 | ||
−29 | −36 | −6 | Hippocampus | LHT | 3.118 | 486 | ||
Control | 21 | −15 | −15 | Hippocampus / parahippocampal gyrus | RHH | 28 | 3.776 | 3838 |
−26 | −14 | −15 | Hippocampus | LHH | 3.278 | 3038 | ||
Nonitem trials–study trials | ||||||||
Control | 24 | −15 | −14 | Hippocampus | RHH | 4.517 | 10461 | |
−26 | −18 | −15 | Hippocampus | LHH | 4.372 | 7599 |
LHH = left hippocampal head; LHT = left hippocampal tail; MDD = major depressive disorder; NA = not applicable; RHH = right hippocampal head.