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. Author manuscript; available in PMC: 2013 Jan 1.
Published in final edited form as: J Immunol. 2011 Nov 23;188(1):57–67. doi: 10.4049/jimmunol.1100783

Figure 1. DEX-specific antibody production in BALB/c mice is long-lived.

Figure 1

(A) Concentration of serum DEX-specific λ+ antibodies in BALB/c mice immunized with DEX, E. cloacae strain MK7 (DEX positive) and strain cBAN (DEX negative). The dotted line defines baseline DEX-specific antibodies in the serum of naïve BALB/c mice. (B) Total numbers of λ+ DEX-specific ASCs in BALB/c mice immunized with purified DEX, E. cloacae strain MK7 or strain cBAN in the (B) spleen and (C) bone marrow. The number of DEX-specific ASCs in the bone marrow was calculated from total BM cells harvested from two femur and tibia per mouse. 10 mice per group were utilized for data derived from experiments A-C. DEX-specific ASCs display restricted isotype usage, 28 days after immunization with DEX or E. cloacae strain MK7 in the (D) spleen and (E) bone marrow. The data from D and E is derived from two independent experiments involving 5 mice per group.