Table 1.
279 African-American breast cancer patients in the present study
| Subject group | Family history of breast and/or ovarian caner |
Number | Age of onset, mean ± SD (years) |
|---|---|---|---|
|
BRCA1/2 mutation - positive |
high | 8 | 43.63 ± 12.52 |
| moderate | 5 | 43.60 ± 4.39 | |
| weak | 6 | 37.17 ± 10.44 | |
| sporadic | 0 | - | |
| total | 19 | 41.58 ± 10.25 | |
|
BRCA1/2 mutation - negative |
high | 11 | 43.19 ± 12.14 |
| moderate | 9 | 49.00 ± 8.19 | |
| weak | 20 | 44.63 ± 11.75 | |
| sporadic | 11 | 38.27 ± 7.24 | |
| total | 51 | 43.68 ± 10.71 | |
|
BRCA1/2 mutation - unknown |
high | 10 | 45.50 ± 11.30 |
| moderate | 15 | 42.27 ± 6.08 | |
| weak | 49 | 44.73 ± 8.77 | |
| sporadic | 135 | 44.04 ± 10.06 | |
| total | 209 | 44.14 ± 9.55 | |
| All | high | 29 | 44.07 ± 11.58 |
| moderate | 29 | 44.59 ± 7.05 | |
| weak | 75 | 44.08 ± 9.83 | |
| sporadic | 146 | 43.59 ± 9.97 | |
| total | 279 | 43.88 ± 9.81 |