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. Author manuscript; available in PMC: 2013 Jan 1.
Published in final edited form as: J Immunol. 2011 Dec 2;188(1):259–269. doi: 10.4049/jimmunol.1101468

Figure 6. RPTPζ is the receptor for MK in B cells.

Figure 6

(A–B) B cells derived from control-129 SvEv mice and RPTPζ deficient mice were purified. (A) RT-PCR, was performed using primers for RPTPζ or HPRT. (B) RPTPζ expression was analyzed by western blot analysis. (C–E) B220+ B cells derived from control-129 SvEv or RPTPζ deficient mice were incubated in the presence or absence of MK (100 ng/ml) (C), MIF (600 ng/ml) (D), or HGF (20 ng/ml) (E) for 16h. Caspase activity was measured by Magic Red apoptosis detection kit. The graphs show an average of at least three independent experiments.