Skip to main content
. Author manuscript; available in PMC: 2013 Jan 1.
Published in final edited form as: J Immunol. 2011 Dec 2;188(1):259–269. doi: 10.4049/jimmunol.1101468

Figure 7. RPTPζ is involved in shaping the mature B cell repertoire.

Figure 7

(A–B) Splenic cells derived from control-129 SvEv mice and RPTPζ deficient mice were purified. (A) Dot plots showing CD21 and CD24 expression on B220+ cells derived from 129SvEv and from RPTPζ deficient mice. Graphs show the average percent and numbers of the mature population in twelve mice. (B) Dot plots showing IgD and IgM expression on B220+ cells derived from the spleen of 129SvEv and RPTPζ deficient mice. (C) Dot plots showing IgD and IgM expression on B220+ cells derived from bone marrow of 129SvEv and RPTPζ deficient mice. The graphs show the average of the percent and numbers of the mature population in seven mice. (D) Dot plots showing IgD and IgM expression on B220+ cells derived from lymph nodes of 129SvEv and RPTPζ deficient mice. The graph summarizes the average number of mature B cells in lymph node derived from 129SvEv and RPTPζ deficient mice, with six mice in each group (E) Dot plots showing CD5 and MAC-1 expression on IgMhigh B220+ cells derived from the peritoneal cavity of 129SvEv and RPTPζ deficient mice.