Table 2. Protocol A: Hemodynamic Parameters and Return of Spontaneous Circulation (ROSC).
Base line | 2 min STD | 5 min STD+SNP | 7 min ACD+ITD | 10 min ACD+ITD+SNP | 12 min ACD+ITD+AB | 15 min ACD+ITD+AB+SNP | No of shocks to ROSC | ROSC to 60m | ||
---|---|---|---|---|---|---|---|---|---|---|
SNP CPR | SBP | 118±14 | 52±6 | 49±12 | 66±14* | 70±16†* | 91±18* | 85±17†* | 1±0.5† | 7/7 (100%)† |
DBP | 85±15 | 18±4 | 19.6±2 | 26±6 | 28±9†* | 40±10* | 38.8±9†* | |||
RA | 2±1 | 6±2 | 5±2 | 4±3 | 4±2 | 12±6* | 9±6 | |||
CPP | 83±15 | 12±3 | 16±2 | 24±5* | 26±6†* | 29±7* | 28.5±7†* | |||
CerPP | 81±16 | 13±5 | 14±2 | 18±8* | 18±8†* | 25±9* | 23±7†* | |||
ICP | 18±2 | 21.5±3 | 21±4 | 23±4 | 23±5 | 33.5±8* | 33±6† | |||
CBF | 403±70 | 141±50* | 127±32* | 164±70* | 200±81* | 270±132* | 365±141*† | |||
S-CPR | Base line | 5 min S-CPR | 10 min S-CPR | 15 min S-CPR | ||||||
SBP | 100±20 | 52±6 | 42±8 | 38±8 | 4±3 | 2/8 (25%) | ||||
DBP | 78±12 | 20±3 | 16±5 | 16±2 | ||||||
RA | 2±2 | 3±2 | 2±2 | 4±3 | ||||||
CPP | 76±11 | 17±3 | 14±3 | 12±3 | ||||||
CerPP | 66±6 | 14±4 | 9±2 | 7±2 | ||||||
ICP | 15±3 | 21±3 | 20±3 | 20±3 | ||||||
CBF | 389±82 | 144±45 | 123±52 | 102±42 |
means p<0.05 within the same group;
means p<0.05 between groups.
SBP: systolic blood pressure; DBP: diastolic blood pressure; RAP: right atrial pressure; CPP: coronary perfusion pressure; CerPP: cerebral perfusion pressure; ICP: intracranial pressure: CBF: carotid blood flow. STD: Standard CPR; SNP: sodium nitroprusside; ACD: active compression decompression CPR; ITD: inspiratory impedance threshold device; AB: abdominal binding.