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. 2011 Nov 20;175(1):11–21. doi: 10.1093/aje/kwr272

Table 4.

Associations of the Most Statistically Significant Single Nucleotide Polymorphisms With Body Mass Indexa (Categorical), by Race/Ethnicity, Southern Community Cohort Study, 2002–2009

Population and Gene rs No. Body Mass Index Category Odds Ratio 95% Confidence Interval P Value
African Americans
    HTR1B rs4140535 <25 1.00
25–29 0.85 0.67, 1.07 0.168
30–34 0.77 0.60, 0.98 0.031
≥35 0.58 0.45, 0.75 2.33 × 10−5
    CYP19A1 rs1902584 <25 1.00
25–29 1.20 0.78, 1.83 0.409
30–34 1.01 0.62, 1.63 0.977
≥35 1.34 0.85, 2.10 0.207
Caucasians
    HTR1B rs4140535 <25 1.00
25–29 0.75 0.59, 0.96 0.021
30–34 0.93 0.73, 1.18 0.538
≥35 0.87 0.68, 1.12 0.274
    CYP19A1 rs1902584 <25 1.00
25–29 0.88 0.55, 1.40 0.592
30–34 1.22 0.78, 1.92 0.382
≥35 1.91 1.26, 2.88 0.002

Abbreviations: CYP19A1, cytochrome P450, family 19; HTR1B, 5-hydroxytryptamine (serotonin) receptor 1B; rs, reference SNP; SNP, single nucleotide polymorphism.

a

Weight (kg)/height (m)2.