Table 4.
Population and Gene | rs No. | Body Mass Index Category | Odds Ratio | 95% Confidence Interval | P Value |
African Americans | |||||
HTR1B | rs4140535 | <25 | 1.00 | ||
25–29 | 0.85 | 0.67, 1.07 | 0.168 | ||
30–34 | 0.77 | 0.60, 0.98 | 0.031 | ||
≥35 | 0.58 | 0.45, 0.75 | 2.33 × 10−5 | ||
CYP19A1 | rs1902584 | <25 | 1.00 | ||
25–29 | 1.20 | 0.78, 1.83 | 0.409 | ||
30–34 | 1.01 | 0.62, 1.63 | 0.977 | ||
≥35 | 1.34 | 0.85, 2.10 | 0.207 | ||
Caucasians | |||||
HTR1B | rs4140535 | <25 | 1.00 | ||
25–29 | 0.75 | 0.59, 0.96 | 0.021 | ||
30–34 | 0.93 | 0.73, 1.18 | 0.538 | ||
≥35 | 0.87 | 0.68, 1.12 | 0.274 | ||
CYP19A1 | rs1902584 | <25 | 1.00 | ||
25–29 | 0.88 | 0.55, 1.40 | 0.592 | ||
30–34 | 1.22 | 0.78, 1.92 | 0.382 | ||
≥35 | 1.91 | 1.26, 2.88 | 0.002 |
Abbreviations: CYP19A1, cytochrome P450, family 19; HTR1B, 5-hydroxytryptamine (serotonin) receptor 1B; rs, reference SNP; SNP, single nucleotide polymorphism.
Weight (kg)/height (m)2.