Table 1.
Phenotypic characteristics of female offspring of Low and High LG mothers.
| Low | High | |
|---|---|---|
| DEVELOPMENT | ||
| In utero T exposure | Less | More |
| Puberty onset | Early | Late |
| MORPHOLOGY | ||
| Anogenital distance | Shorter | Longer |
| EPIGENETICS | ||
| ERα MPOA | More methylation | Less methylation |
| GR | More methylation | Less methylation |
| Less histone acetylation | More histone acetylation | |
| BRAIN | ||
| ERα VMH and AVPv | More | Less |
| ERα MPOA | Less | More |
| GnRH neurons | More | Less |
| GR hippocampus | Less | More |
| HORMONES | ||
| LH | More | Less |
| Progesterone | More | Less |
| BEHAVIORS | ||
| Maternal care | Less | More |
| Sexual behavior | More | Less |
| Stress response | More | Less |