Table 4.
Prospective studies on the effects of diet and exercise in NAFLD
| Author | Year | N | Indication | Additional therapy | Duration (months) | Histologic Improvement | ||
|---|---|---|---|---|---|---|---|---|
| NAS | Steatosis | Fibrosis | ||||||
| Promrat117 RCT | 2010 | 31 | NASH | 12 | + | + | − | |
| Hickman118 | 2004 | 14 | NAFLD | 6 | + | + | ||
| Nakamuta27 | 2005 | 11 | Pre-transplant | Bezafibrate | ½–2 | + | ||
| Chen122 | 2008 | 23 | Pre-transplant | 1–3 | + | |||
NAFLD, non-alcoholic fatty liver disease; NASH, non-alcoholic steatohepatitis; NAS, NAFLD activity score; RCT, randomized controlled trial.